Name: Xudong Qu
Subjects:Chemical BIology
Department: School of Pharmaceutical Sciences
College appointment: Professor
Email: quxd@whu.edu.cn
Telephone: 862768753529
Fax: 862768753529
Web-page:
◆Background/Biography:
·Education:
2007.9-2008.10: Postdoctoral Associate, Department of chemistry, Massachusetts Institute of Technology, USA
2002.9-2007.7: Ph.D., Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, China
1998.-2002: B.S., Department: Chemistry, East China Normal University, China
·Honors & Awards:
2014. National excellent youth scholar
2013. New Century Excellent Talents of Chinese Ministry of Education
2012. Luojia distinguished professorship of Wuhan university
◆Teaching:
Chemical Biology
◆Research interests:
Synthetic biology, Natural products biosynthesis
◆Publications:
1. Chang C, Huang R, Yan Y, Ma H, Dai Z, Zhang B, Deng Z, Liu W, Qu X*. Uncovering the Formation and Selection of Benzylmalonyl-CoA from the Biosynthesis of Splenocin and Enterocin Reveals a Versatile Way to Introduce Amino Acids into Polyketide Carbon Scaffolds. J Am Chem Soc. 2015, 137, 4183−4190.
2. Wu Q, Wu Z, Qu X*, Liu W*. Investigations into pyrroindomycin biosynthesis indicate a uniform paradigm for complex tetramate tetronate formation. J Am Chem Soc 2012, 134, 17342-17345.
3. Qu X*, Pang B, Zhang Z, Chen M, Wu Z, Zhao Q, Zhang Q, Wang Y, Liu Y, Liu W*. Caerulomycins and collismycins share a common paradigm for 2, 2’-bipyridine biosynthesis via an unusual hybrid polyketide-peptide assembly logic. J Am Chem Soc 2012, 134, 9038-9041.
4. Qu X, Lei C, Liu W*. Transcriptome mining of active biosynthetic pathways for natural product discovery. Angew Chem Int Ed 2011, 50, 9651-9654.
5. Runguphan W#, Qu X#, O’Connor S* (#co-first author). Integrating carbon halogen bond formation into medicinal plant metabolism. Nature 2010, 468, 461-464.