Faculty

Xudong Qu
Author:  Date:January 6, 2016  Click:

Name: Xudong Qu

SubjectsChemical BIology

Department: School of Pharmaceutical Sciences

College appointment: Professor

Email: quxd@whu.edu.cn

Telephone: 862768753529

Fax: 862768753529

Web-page:

 

Background/Biography:

·Education:

2007.9-2008.10: Postdoctoral Associate, Department of chemistry, Massachusetts Institute of Technology, USA

2002.9-2007.7: Ph.D., Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, China

1998.-2002: B.S., Department: Chemistry, East China Normal University, China

 

·Honors & Awards

2014. National excellent youth scholar

2013. New Century Excellent Talents of Chinese Ministry of Education

2012. Luojia distinguished professorship of Wuhan university

 

Teaching:

Chemical Biology

 

Research interests:

Synthetic biology, Natural products biosynthesis

 

Publications:

1. Chang C, Huang R, Yan Y, Ma H, Dai Z, Zhang B, Deng Z, Liu W, Qu X*. Uncovering the Formation and Selection of Benzylmalonyl-CoA from the Biosynthesis of Splenocin and Enterocin Reveals a Versatile Way to Introduce Amino Acids into Polyketide Carbon Scaffolds. J Am Chem Soc. 2015, 137, 4183−4190.

2. Wu Q, Wu Z, Qu X*, Liu W*. Investigations into pyrroindomycin biosynthesis indicate a uniform paradigm for complex tetramate tetronate formation. J Am Chem Soc 2012, 134, 17342-17345.

3. Qu X*, Pang B, Zhang Z, Chen M, Wu Z, Zhao Q, Zhang Q, Wang Y, Liu Y, Liu W*. Caerulomycins and collismycins share a common paradigm for 2, 2’-bipyridine biosynthesis via an unusual hybrid polyketide-peptide assembly logic. J Am Chem Soc 2012, 134, 9038-9041.

4. Qu X, Lei C, Liu W*. Transcriptome mining of active biosynthetic pathways for natural product discovery. Angew Chem Int Ed 2011, 50, 9651-9654.

5. Runguphan W#, Qu X#, O’Connor S* (#co-first author). Integrating carbon halogen bond formation into medicinal plant metabolism. Nature 2010, 468, 461-464.