Name: Jianqing Yu
Subjects：Medicinal Chemistry of Natural Products
Department: TCM & Natural Products
College appointment: College of Pharmaceutical Sciences
·Education: PhD in Biochemistry and Molecular Biology, College of Life Sciences, Wuhan University, China (2002-2005); Master of Medicine in Hubei University of Chinese Medicine, China (1998-2000); Bachelor of Medicine in Hubei University of Chinese Medicine, China (1984-1988)
◆Teaching: Natural Medicinal Chemistry; Pharmacognosy
◆Research interests: Searching for bioactive compounds from medicinal plants; elucidating the mechanisms of action of natural products with promising bioactivities including anticancer and overcoming chemoresistance in cancer.
1. Li J, Wang Y, Lei J, Hao Y, Yang Y, Yang C, Yu J* (2014). Sensitisation of ovarian cancer cells to cisplatin by flavonoids from Scutellaria barbata. Natural Product Research 28(10): 683–689.
2. Yu J, Bao W, Lei J (2013). Emodin regulates apoptotic pathway in human liver cancer cells. Phytotherapy Research 27(2): 251–257.
3. Luo T#, Yu J#, Nguyen J#, Wang CR, Bristow RG, Jaffray DA, Zhou XZ, Lu KP, Lu QB* (2012). Electron transfer-based combination therapy of cisplatin with tetramethyl-p-phenylenediamine for ovarian, cervical, and lung cancers. Proc. Natl. Acad. Sci. USA (PNAS) 109：10175–10180.
4. Ding C, Zhang W, Li J, Lei J, Yu J* (2013). Cytotoxic constituents of ethyl acetate fraction from Dianthus superbus. Natural Product Research 27: 1691–1694.
5. Yu J, Yin Y, Lei J, Zhang X, Chen W, Ding C, Wu S, He X, Liu Y, Zou G (2012). Activation of apoptosis by ethyl acetate fraction of ethanol extract of Dianthus superbus in HepG2 cell line. Cancer Epidemiology 36: e40–e45.
6. Lei J, Yu J*, Yin Y, Liu Y, Zou G (2012). Alantolactone induces activation of apoptosis in human hepatoma cells. Food and Chemical Toxicology 50: 3313–3319.
7. Yu J, Lei J, Zhang X, Yu H, Tian D, Liao Z, Zou G (2011). Anticancer, antioxidant and antimicrobial activities of the essential oil of Lycopus lucidus Turcz. var. hirtus Regel. Food Chemistry 126: 1593–1598.
8. Lei J, Yu J*, Yu H, Liao Z. Composition, cytotoxicity and antimicrobial activity of essential oil from Dictamnus dasycarpus. Food Chemistry, 2008, 107: 1205–1209.
9. Yu J, Liu H, Tian D, Liu Y, Lei J, Zou G (2007). Changes in mitochondrial membrane potential and reactive oxygen species during wogonin-induced cell death in human hepatoma cells. Hepatology Research 37: 68–76.
10. Yu J, Liu H, Lei J, Tan W, Hu X, Zou G (2007). Antitumor activity of chloroform fraction of Scutellaria barbata and its active constituents. Phytotherapy Research 21: 817–822.
11. Yu J, Liao Z, Lei J, Hu X (2007). Antioxidant and cytotoxic activities of various fractions of ethanol extract of Dianthus superbus. Food Chemistry 104: 1215-1219.
12. Yu J, Liao Z, Cai X, Lei J, Zou G (2007). Composition, antimicrobial activity and cytotoxicity of essential oils from Aristolochia mollissima. Environmental Toxicology and Pharmacology 23: 162–167.