Name: Jianqing Yu
Subjects：Medicinal Chemistry of Natural Products
Department: TCM & Natural Products
College appointment: College of Pharmaceutical Sciences
Email: jqyu@whu.edu.cn
Telephone: 027-68759983
Fax:027-68759850
◆Background/Biography:
·Education: PhD in Biochemistry and Molecular Biology, College of Life Sciences, Wuhan University, China (2002-2005); Master of Medicine in Hubei University of Chinese Medicine, China (1998-2000); Bachelor of Medicine in Hubei University of Chinese Medicine, China (1984-1988)
◆Teaching: Natural Medicinal Chemistry; Pharmacognosy
◆Research interests: Searching for bioactive compounds from medicinal plants; elucidating the mechanisms of action of natural products with promising bioactivities including anticancer and overcoming chemoresistance in cancer.
◆Publications:
1. Li J, Wang Y, Lei J, Hao Y, Yang Y, Yang C, Yu J* (2014). Sensitisation of ovarian cancer cells to cisplatin by flavonoids from Scutellaria barbata. Natural Product Research 28(10): 683–689.
2. Yu J, Bao W, Lei J (2013). Emodin regulates apoptotic pathway in human liver cancer cells. Phytotherapy Research 27(2): 251–257.
3. Luo T#, Yu J#, Nguyen J#, Wang CR, Bristow RG, Jaffray DA, Zhou XZ, Lu KP, Lu QB* (2012). Electron transfer-based combination therapy of cisplatin with tetramethyl-p-phenylenediamine for ovarian, cervical, and lung cancers. Proc. Natl. Acad. Sci. USA (PNAS) 109：10175–10180.
4. Ding C, Zhang W, Li J, Lei J, Yu J* (2013). Cytotoxic constituents of ethyl acetate fraction from Dianthus superbus. Natural Product Research 27: 1691–1694.
5. Yu J, Yin Y, Lei J, Zhang X, Chen W, Ding C, Wu S, He X, Liu Y, Zou G (2012). Activation of apoptosis by ethyl acetate fraction of ethanol extract of Dianthus superbus in HepG2 cell line. Cancer Epidemiology 36: e40–e45.
6. Lei J, Yu J*, Yin Y, Liu Y, Zou G (2012). Alantolactone induces activation of apoptosis in human hepatoma cells. Food and Chemical Toxicology 50: 3313–3319.
7. Yu J, Lei J, Zhang X, Yu H, Tian D, Liao Z, Zou G (2011). Anticancer, antioxidant and antimicrobial activities of the essential oil of Lycopus lucidus Turcz. var. hirtus Regel. Food Chemistry 126: 1593–1598.
8. Lei J, Yu J*, Yu H, Liao Z. Composition, cytotoxicity and antimicrobial activity of essential oil from Dictamnus dasycarpus. Food Chemistry, 2008, 107: 1205–1209.
9. Yu J, Liu H, Tian D, Liu Y, Lei J, Zou G (2007). Changes in mitochondrial membrane potential and reactive oxygen species during wogonin-induced cell death in human hepatoma cells. Hepatology Research 37: 68–76.
10. Yu J, Liu H, Lei J, Tan W, Hu X, Zou G (2007). Antitumor activity of chloroform fraction of Scutellaria barbata and its active constituents. Phytotherapy Research 21: 817–822.
11. Yu J, Liao Z, Lei J, Hu X (2007). Antioxidant and cytotoxic activities of various fractions of ethanol extract of Dianthus superbus. Food Chemistry 104: 1215-1219.
12. Yu J, Liao Z, Cai X, Lei J, Zou G (2007). Composition, antimicrobial activity and cytotoxicity of essential oils from Aristolochia mollissima. Environmental Toxicology and Pharmacology 23: 162–167.
